;; Akemann W, Knopfel T. Interaction of Kv3 potassium channels and
;; resurgent sodium current influences the rate of spontaneous firing of
;; Purkinje neurons. J Neurosci. 2006 Apr 26;26(17):4602-12.

(nemo-model Ih

  ((input v )
	     
   (const Vrest   = -68)
   (const celsius = 24)
   
   (const temp_adj = (pow (3 ((celsius - 22) / 10))))

   (component (type ion-channel) (name Ih)
	      
	      (component (type gate)
			 
			 ;; rate functions
			 
			 (defun Ih_inf (v)
			   (let ((cvn   90.1)
				 (ckn   -9.9))
			     (1.0 / (1.0 + exp (neg ((v + cvn) / ckn) )))))
			 
			 (defun Ih_tau (v)   
			   (let ((cct  190)
				 (cat  720)
				 (cvt  81.5)
				 (ckt  11.9))
			     (cct + (cat * exp (neg (pow (((v + cvt) / ckt) 2)))))))
			 
			 (hh-ionic-gate 
			  (Ih  ;; ion name: exported variables will be of the form {ion}_{id}
			   (initial-m (Ih_inf (Vrest)))
			   (m-power   1)
			   (h-power   0)
			   (m-inf     (Ih_inf (v)))
			   (m-tau     (Ih_tau (v) / temp_adj))
			   ))
			 
			 )

	      (component (type pore)
			 (const  gbar_Ih  = 0.0002)
			 (output gbar_Ih ))
	      
	      (component (type permeating-ion) (name non-specific)
			 (const e_Ih = -30)
			 (output e_Ih ))
	      
	      ) ;; end Ih current
	    
   ))