;; Akemann W, Knopfel T. Interaction of Kv3 potassium channels and
;; resurgent sodium current influences the rate of spontaneous firing of
;; Purkinje neurons. J Neurosci. 2006 Apr 26;26(17):4602-12.

(nemo-model Kv1

  ((input v)

   (const Vrest   = -68)
	     
   (const celsius = 24)
   
   (const temp_adj = (pow (3 ((celsius - 22) / 10))))

   (component (type ion-channel) (name Kv1)
	      
	      (component (type gate)
			 
			 ;; rate functions
			 (defun Kv1_amf (v) 
			   (let ((cma 0.12889)
				 (cka -33.90877)
				 (cva 45))
			     (cma * (exp (neg ((v + cva) / cka))))))
			 
			 (defun Kv1_bmf (v)
			   (let ((cmb   0.12889)
				 (ckb   12.42101)
				 (cvb   45))
			     (cmb * (exp (neg ((v + cvb) / ckb))))))
			 
			 (hh-ionic-gate 
			  (Kv1  ;; ion name: exported variables will be of the form {ion}_{id}
			   (initial-m (Kv1_amf (Vrest) / (Kv1_amf (Vrest) + Kv1_bmf (Vrest))))
			   (m-power   4)
			   (h-power   0)
			   (m-alpha   (temp_adj * Kv1_amf (v) ))
			   (m-beta    (temp_adj * Kv1_bmf (v) ))))
			 
			 )
	      
	      (component (type pore)
			 (const  gbar_Kv1  = 0.011)
			 (output gbar_Kv1 ))
	      
	      (component (type permeating-ion) (name k)
			 (const e_Kv1 = -85)
			 (output e_Kv1 ))
	      
	      ) ;; end Kv1 current
   
	    
   ))