(nemo-model Golgi_KA

  (
   (input v celsius)

   (defun sigm (x y) (1 / (exp (x / y) + 1)))

   (component (type ionic-current) (name KA )
	      
	      (component (type gate)

			 ;; rate constants

			 (Q10 = (pow (3 ((celsius - 25.5) / 10))))

			 (const Aalpha_a  = 0.8147)
			 (const Kalpha_a  = -23.32708)
			 (const V0alpha_a = -9.17203)
			 (const Abeta_a   = 0.1655)
			 (const Kbeta_a   = 19.47175)
			 (const V0beta_a  = -18.27914)

			 (const Aalpha_b  = 0.0368)
			 (const Kalpha_b  = 12.8433)
			 (const V0alpha_b = -111.33209)
			 (const Abeta_b   = 0.0345)
			 (const Kbeta_b   = -8.90123)
			 (const V0beta_b  = -49.9537)

			 (const V0_ainf = -38)
			 (const  K_ainf = -17)

			 (const V0_binf   = -78.8)
			 (const K_binf    = 8.4)

			 
			 ;; rate functions

			 (defun alpha_a (v Q10)
			   (Q10 * Aalpha_a * sigm((v - V0alpha_a) Kalpha_a)))

			 (defun beta_a (v Q10)
			   (Q10 * (Abeta_a / exp((v - V0beta_a) / Kbeta_a))))

			 (defun alpha_b (v Q10)
			   (Q10 * Aalpha_b * sigm((v - V0alpha_b) Kalpha_b)))

			 (defun beta_b (v Q10)
			   (Q10 * Abeta_b * sigm((v - V0beta_b) Kbeta_b)))



			 (a_inf = (1 / (1 + exp ((v - V0_ainf) / K_ainf)))) 
			 (tau_a = (1 / (alpha_a (v Q10) + beta_a (v Q10)) ))
			 (b_inf = (1 / (1 + exp ((v - V0_binf) / K_binf))))
			 (tau_b = (1 / (alpha_b (v Q10) + beta_b (v Q10)) ))


			 (hh-ionic-gate 
			  (KA  ;; ion name: exported variables will be of the form {ion}_{id}
			   (initial-m  (a_inf))
			   (initial-h  (b_inf))
			   (m-power    3)
			   (h-power    1)
			   (m-inf      a_inf)
			   (m-tau      tau_a)
			   (h-inf      b_inf)
			   (h-tau      tau_b)
			   ))

			 )

	      	      
	      (component (type pore)
			 (const  gbar  = 0.008)
			 (output gbar ))

	      
	      (component (type permeating-ion) (name k)
			 (const e = -84.69)
			 (output e ))
	      
	      ) ;; end KA current
	      

	      (component (type voltage-clamp) (name KA)
           
			 (const vchold   = -71)
			 (const vcbase   = -69)
			 (const vcinc    = 10)
			 (const vcsteps  = 8)
			 (const vchdur   = 30)
			 (const vcbdur   = 100)
           
			 (output vchold vcbase vcinc vcsteps vchdur vcbdur)
			 )

))